Coax has the fields contained within the cable, open-wire does not.
Structures, people, and critters in proximity to coax don't matter. It's a
different matter with open-wire. Open wire usually requires a BalUn, as
well.
The WWII, British, CH radar (circa 50MHz), used open wire feeders to the
transmitting antennas. The transmitters were a Marconi-EMI television
design, of a few hundred kW, modified for pulse modulation, one of the
reasons for killing the early British TV service.
The guy I knew who'd worked on it described how the routing at one site,
around the edge of the field, with several corners, to conceal the feeders
from the air, couldn't be made to work, and they had to go direct, making
a beautiful sighting line to the camouflaged transmitter.