Wheatstone measurement bridge is kind of very accurate measurement approachdue differential measurement. But it is also very complex if impedances inbranches of the bridge are not pure resistive. On the other hand, pure resistive bridge can be simulated if imaginary parts are set to zero.
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http://www.cirvirlab.com/index.php/electric/102-wheatstone-measurement-bridge-simulation.html
http://www.cirvirlab.com/simulation/wheatstone_measurement_bridge_online.php