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Pixel sensor of neural recording

I am wondering if instead of using a MicroElectrode Array (MEA) for neural recording, we can use some different circuits like: Voltage to frequency Converter or Digital sensors that are connected directly to the electrode
Ps: the array of electrodes have pitch around 10x10microm^2.
Thanks in advance.
 

hevans1944

Hop - AC8NS
I suppose anything is possible in this age of nano-electronic circuitry. For forum members wishing to explore the possibilities, here is an article with background information. Are we ready yet to grow computers in a Petri dish?
 
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